Gazprom Neft Companу Group has adapted systems engineering methods and other practices for the oil and gas industry. Systems engineering approaches have been reflected in the framework of organizational transformation. The main goal of the transformation was to create responsibility centers for solving problems related to the creation, design and support at the stages of construction and operation of complex technical systems of ground arrangement of the entire perimeter of exploration and production. Today, conditions in the industry create a high demand for the accumulation of knowledge for the subsequent synthesis and circulation of successful engineering solutions. To ensure the technological sovereignty and leadership of the company, there is a need to develop engineering as a process of engineering management that ensures the formation of an integration layer for the implementation of the results of innovative activities and technical policy in production. The results of the organizational transformation and the practical application of individual systems engineering practices build a scheme that ensures the implementation and circulation of technological development projects, forming a continuous cycle of knowledge accumulation. The first results of the Eastern Siberia projects show significant changes in the processes: speed of implementation, quality and continuity of technical solutions when moving projects from stage to stage.